Cancer Prevention Clinical Trials Network (CP-CTNet): CP-CTNet Sites (UG1 Clinical Trial Required) RFA-CA-24-024
Sponsor: NIHInternal Deadline: 08/30/2024Institutional Submission Limit: 1Sponsor Deadline: 10/31/2024Program Website
Through this NOFO, the National Cancer Institute (NCI) proposes and will support the Cancer Prevention Clinical Trials Network (CP-CTNet) sites, for which the goals are as follows:
Design and conduct of early phase clinical trials to assess the safety, tolerability, and cancer preventive potential of agents and interventions of varying classes, many of which target molecules or processes known to be important during carcinogenesis. These trials include phase 0 (micro-dosing), phase I (dose-finding), and phase II (preliminary efficacy) clinical trials;
Characterization of the effects of these agents and interventions on their molecular targets, as well as on other biological events associated with cancer development (such as cell proliferation, apoptosis, growth factor expression, oncogene expression, immune response) and correlation of these effects with clinical endpoints.
Development of further scientific insights into the mechanisms of cancer prevention by the agents examined, including the development of novel potential markers as determinants of response.
CP-CTNet consists of two types of components:
CP-CTNet Sites; and
One CP-CTNet Data Management, Auditing, and Statistical Center (DMASC) (covered by companion NOFO, RFA-CA-24-025)
The CP-CTNet Sites will provide scientific leadership in development and conduct of early phase cancer prevention clinical trials as well as in the management and analysis of the data.
Submission Process
Limited submissions MUST be coordinated with the Office of the Vice President for Research.
If interested in applying for this opportunity, please combine the following items into a single PDF and email to resdev@mailbox.sc.edu by 5pm on the INTERNAL DEADLINE above:
- Cover page with grant program name & number (if applicable) to which you are applying, your project title, PI (name, department/unit, & email), and list of co-PIs/key collaborators (name & department/unit)
- a two-page project abstract addressing key components/criteria for this specific grant program
- a 2-3 page CV/biosketch for the PI (SCiENcv preferred)