RFA-AI-27-012: Coccidioidomycosis Collaborative Research Centers (P01 Clinical Trial Not Allowed)

Sponsor: NIH, NIAID
Internal Deadline: 05/13/2026
Institutional Submission Limit: 1
Program Website

The purpose of the notice of funding opportunity (NOFO) is to solicit applications for a Coccidioidomycosis Collaborative Research Centers (CCRC) program. This new initiative will establish highly collaborative, multi-disciplinary, research teams to conduct translational and clinical research to support the development of a Valley fever vaccine as outlined in NIAID’s Strategic Plan for Research to Develop a Valley fever Vaccine.

This initiative will establish Coccidioidomycosis Collaborative Research Centers (CCRCs) to conduct multi-disciplinary research aligned with the priorities outlined in NIAID’s Strategic Plan for Research to Develop a Valley fever Vaccine. It is expected that the CCRCs will leverage unique research resources and patient populations from endemic regions to advance the field.

It is envisioned that overarching themes could include, but are not limited to:

• Discovery and validation of novel vaccine and/or immunomodulatory targets and pathways


• Identification and validation of correlates of immune protection


• Diagnostic development to support vaccine testing

Collaborative Interdisciplinary Teams

The scope of this work necessitates that multidisciplinary teams be formed that can pursue coordinated activities that can bridge translational and clinical research. To enhance the overall quality and success of the Center, each CCRC should include distinct expertise. As an example, a CCRC focused on elucidating mechanism of disease severity, dissemination and correlates of protection could bring together investigators and clinicians with expertise in fungal biology, genetics, computational genomics, immunology and access to patient specimens and or cohorts. As a second example, a CCRC focused on identifying and validating new strategies for vaccine development could bring together investigators and clinicians with expertise in fungal biology, genomics, immunology, vaccinology and access to patient specimens and or cohorts.

 

Only one application per institution (normally identified by having a unique entity identifier (UEI) number or NIH IPF number) is allowed.

Submission Process

Limited submissions MUST be coordinated with the Office of the Vice President for Research.

If interested in applying for this opportunity, please combine the following items into a single PDF and email to resdev@mailbox.sc.edu by 5pm on the INTERNAL DEADLINE above:

• Cover page with grant program name & number (if applicable) to which you are applying, your project title, PI (name, department/unit, & email), and list of co-PIs/key collaborators (name & department/unit)
• a two-page project abstract addressing key components/criteria for this specific grant program
• a 2-3 page CV/biosketch for the PI (SCiENcv preferred)