In this study, orthopedic colleagues aimed to evaluate how tranexamic acid (TXA) affects blood loss during different types of elective cervical spine surgeries.

The purpose of this study was to assess the impact of intravenous tranexamic acid (TXA), a medication used to treat and prevent excessive blood loss, on blood loss outcomes in anterior, posterior, and combined approaches for elective cervical spine surgery. Limited studies have examined the efficacy of TXA in this type of surgery. A retrospective cohort study was conducted on patients receiving elective cervical spine surgeries from 2011 to 2017. The use of TXA was found to significantly reduce perioperative blood loss and postoperative drain output in posterior approach surgery, but not in anterior or combined surgery. Its use was also associated with a decrease in intraoperative and postoperative blood loss.

Money, A. J., Dumont, G., Sheppard, S., Jackson, J. B., 3rd, Spitnale, M., Bakaes, Y., Gauthier, C., & Grabowski, G. (2024). A Retrospective Comparative Analysis on the Effect of Tranexamic Acid to Reduce Perioperative Blood Loss in Patients Undergoing Cervical Spine Surgery. Clinical spine surgery, 37(7), E330–E334.