Overview

The TEDDY study - The Environmental Determinants of Diabetes in the Young - is a large scale, international, multi-center prospective observational study aimed at identifying environmental and behavioral factors that trigger development of Type 1 Diabetes in children. A large cohort of children, known to be at high risk for development of Type 1 Diabetes based on genetic profile, is being followed from birth to age 15 or diagnosis of the disease, whichever comes first. Physical Activity is hypothesized to be one of a cluster of variables that may influence disease risk, influencing the outcome either independently or by mediating the effect of other characteristics such as diet and weight status. Physical activity is being measured annually beginning at age 5 by accelerometry and logs. The CPARG team is providing expertise in management and analysis of the physical activity data. In addition, CPARG investigators will provide guidance regarding creation of physical activity variables for analysis, oversight/quality control of physical activity data, and conceptualization of data analyzed that include physical activity variables. For more information on the TEDDY study, please visit https://teddy.epi.usf.edu/TEDDY/index.htm.

Project Details

Timeline: 2014-2016
Funding Source: NIH (subcontract with University of South Florida)
Principal Investigator: Russell R. Pate
Co-Investigator: Kerry McIver

Publications

Kerry L. McIver, Russell R. Pate, Marsha Dowda, Suzanne Bennett Johnson, Jimin Yang, Martha Butterworth, Xiang Liu, "Cross-Country Comparisons of Physical Activity and Sedentary Behavior among 5-Year-Old Children", International Journal of Pediatrics, vol. 2020, Article ID 7912894, 9 pages, 2020. [pdf]